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Clinical and Experimental Otorhinolaryngology > Accepted Articles
doi: https://doi.org/10.21053/ceo.2023.00023    [Accepted]
Predictors for Difficult Laryngeal Exposure in Suspension Laryngoscopy: A Systematic Review and Meta-Analysis
Mengshu Wang1,2,3 , Yong Liu1,2,3,4 , Yuanzheng Qiu1,2,3,4 , Huihong Chen1,2,3 , Wang Liwen5 , Donghai Huang1,2,3 , Xin Zhang1,2,3,4 , Guo Li1,2,3
1Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, Hunan 410008, People’s Republic of China
2Otolaryngology Major Disease Research, Key Laboratory of Hunan Province, 87 Xiangya Road, Changsha, Hunan 410008, People’s Republic of China
3Clinical Research Center for Pharyngolaryngeal Diseases and Voice Disorders in Hunan Province, 87 Xiangya Road, Changsha, Hunan 410008, People’s Republic of China
4National Clinical Research Center for Geriatric Disorders (Xiangya Hospital), 87 Xiangya Road, Changsha, Hunan 410008, People’s Republic Of China
5Department of Hematology, Third Xiangya Hospital, Central South University, Changsha, Hunan, China,410013
Correspondence  Guo Li ,Tel: +860731-84327469, Email: liguoent@csu.edu.cn
Received: October 26, 2023; Revised: April 8, 2024   Accepted: April 25, 2024.  Published online: April 25, 2024.
ABSTRACT
Objectives/Hypothesis
Many researchers have investigated parameters that could independently predict difficult laryngeal exposure (DLE) in suspension laryngoscopy; however, inconsistent results and conclusions have been reported in previous studies. We conducted a meta-analysis of the existing literature to determine the parameters that are significant for a standardized preoperative DLE prediction system.
Methods
The literature was retrieved systematically from PubMed, Embase, Web of Science, China national knowledge infrastructure (CNKI), and Wangfang until October 2022. In eligible studies, data were extracted and analyzed using the R language, and effective measures were odds ratios with 95% confidence intervals (CIs) for dichotomous variables and mean differences (MD) with 95% CIs for continuous variables.
Results
The search yielded 1574 studies, of which eighteen involving 2263 patients were included. Pooled analysis demonstrated that patients with DLE during microsurgery are often men (OR =1.73, 95% CI = [1.16, 2.57]); older age (MD = 5.47 years, 95% CI = [2.44, 8.51]); high body mass index (BMI; MD = 1.19Kg/m2, 95% CI = [0.33, 2.05]); bullnecked (MD =2.50cm, 95% CI = [1.56, 3.44]); limited mouth opening (MD = -0.52cm, 95% CI = [-0.88, -0.15]); limited neck flexibility (MD = -10.05cm, 95% CI = [-14.10,-6.00]); specific anatomical characteristics; and modified Mallampati’s index or test (OR = 3.37, 95% CI = [2.07, 5.48]).
Conclusions
Our study made a comprehensive and systematic analysis of The DLE relevant factors. Gender, age, body mass index(BMI), neck circumference (NC), modified Mallampati’s index(MMI), inter-incisor gap(IIG), hyoid-mental distance (HMD), thyroid-mental distance (TMD), sterno-mental distance (SMD), and flexion-extension angle were eventually identified as highly correlated factors for DLE.
Keywords: difficult laryngeal exposure, suspension laryngoscopy, anterior commission, microlaryngoscopy
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