Clinical and Experimental Otorhinolaryngology

Review

April 13, 2018

Samter’s Triad: State of the Art

Sung-Dong Kim, Kyu-Sup Cho

Clin Exp Otorhinolaryngol. 2018;11(2):71-80.

Samter’s triad (ST) is nonallergic hypersensitivity reaction.
We review the pathophysiology, diagnosis, and therapeutic options of ST.
Aspirin desensitization reduces nasal symptoms and the need for continuous medication and surgery.
The patients with ST should receive aspirin desensitization after endoscopic sinus surgery.

Review

April 14, 2018

A Systematic Review of Benefit of Silicone Intubation in Endoscopic Dacryocystorhinostomy

Min Gyu Kang, Woo Sub Shim, Dong Keun Shin, Joo Yeon Kim, Ji-Eun Lee, Hahn Jin Jung

Clin Exp Otorhinolaryngol. 2018;11(2):81-88.

There is some controversy regarding the use of silicone stenting in endoscopic dacryocystorhinostomy.
Meta-analysis showed no significant differences with regard to the surgical success rate and the postoperative complications.
There was no clear evidence showing that stent intubation during endoscopic dacryocystorhinostomy is superior to nonintubation.

Original Article

December 1, 2017

Endoscope-Assisted Cochlear Implantation

Enis Alpin Güneri, Yüksel Olgun

Clin Exp Otorhinolaryngol. 2018;11(2):89-95.

● Surgical landmarks can be more easily identified with the aid of endoscopes.
● Endoscopic evaluation can reduce risk of complications by minimizing surgical orientation.
● Axial computed tomography scans are useful to determine if the surgical exposure of the round window is difficult.

Original Article

January 10, 2018

Clinical Characteristics and Short-term Outcomes of Acute Low Frequency Sensorineural Hearing Loss With Vertigo

Myung Jin Park, Sang Hoon Kim, Sung Su Kim, Seung Geun Yeo

Clin Exp Otorhinolaryngol. 2018;11(2):96-101.

The prognosis in patients with acute low frequency hearing loss is poorer in those with than without vertigo.
The hearing recovery rate in patients with vertigo tends to be higher in those treated with steroids than with diuretics alone.

Original Article

January 9, 2018

Relationship of Vertigo and Postural Instability in Patients With Vestibular Schwannoma

Gi-Sung Nam, Chan Min Jung, Ji Hyung Kim, Eun Jin Son

Clin Exp Otorhinolaryngol. 2018;11(2):102-108.

Postural instability is prevalent in vestibular schwannoma (VS) patients with acute onset and insidious onset vestibular symptoms.
Computerized dynamic posturography parameters were correlated with the tumor size and caloric weakness, but not with acute or insidious onset of vertigo.
VS patients with insidious onset of vertigo symptoms tended to show increased canal weakness and postural instability.
Further vestibular evaluation would be useful even in VS patients who do not experience acute vertigo episodes.

Original Article

January 6, 2018

Impact of Nicotine Exposure on Hair Cell Toxicity and Embryotoxicity During Zebrafish Development

Myung Hoon Yoo, Yoon Chan Rah, Saemi Park, Soonil Koun, Gi Jung Im, Sung Won Chae, Hak Hyun Jung, June Choi

Clin Exp Otorhinolaryngol. 2018;11(2):109-117.

Zebrafish is an effective model for the study of embryotoxicity.
Nicotine can affect embryogenesis during zebrafish development.
Nicotine induce dose-dependent hair cell toxicity in embryos.

Original Article

February 14, 2018

The Allele 2 of the VNTR Polymorphism in the Gene That Encodes a Natural Inhibitor of IL-1β, IL-1RA Is Favorably Associated With Chronic Otitis Media

Maja Živković, Ivana Kolić, Snežana Jesić, Ana Jotić, Aleksandra Stanković

Clin Exp Otorhinolaryngol. 2018;11(2):118-123.

▪ The allele 2 of interleukin-1 receptor antagonist variable number tandem repeat is favorably associated with chronic otitis media.
▪ The interleukin-1 receptor antagonist allele frequencies were significantly different with regard to cholesteatoma.

Original Article

January 11, 2018

Clusterin Induces MUC5AC Expression via Activation of NF-κB in Human Airway Epithelial Cells

Chang Hoon Bae, Hyung Gyun Na, Yoon Seok Choi, Si-Youn Song, Yong-Dae Kim

Clin Exp Otorhinolaryngol. 2018;11(2):124-132.

Clusterin induces MUC5AC expression.
Clusterin was abundantly present in the epithelium of nasal polyp.
Clusterin induces MUC5AC expression via the activation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB).

Original Article

February 8, 2018

Impact and Modulations of Peripheral and Edaphic B Cell Subpopulations in Chronic Rhinosinusitis With Nasal Polyposis

Pascal Ickrath, Norbert Kleinsasser, Xin Ding, Christian Ginzkey, Niklas Beyersdorf, Thomas Kerkau, Rudolf Hagen, Stephan Hackenberg

Clin Exp Otorhinolaryngol. 2018;11(2):133-140.

▪ Memory cells present the main B cell subpopulations in nasal polyps.
▪ Regulatory B cells and mature B cells significantly decrease in nasal polyps compared to peripheral blood mononuclear cell.
▪ Reduced regulatory B cells frequencies or high frequencies of memory B cells may cause T cell dysfunction.

Original Article

October 11, 2017

Comparison of Characteristics According to Reflux Type in Patients With Laryngopharyngeal Reflux

Jun Seok Lee, Ah Ra Jung, Jung Min Park, Myung Jin Park, Young Chan Lee, Young-Gyu Eun

Clin Exp Otorhinolaryngol. 2018;11(2):141-145.

Acid, nonacid, and mixed types of LPR were determined in 83 patients with 24-hour MII pH monitoring.
No LPR patients had acid reflux.
Clinical characteristics between patients with nonacid and mixed LPR did not differ.

Original Article

December 28, 2017

Effect of Topical Propolis on Wound Healing Process After Tonsillectomy: Randomized Controlled Study

Jeong Hwan Moon, Min Young Lee, Young-Jun Chung, Chung-Ku Rhee, Sang Joon Lee

Clin Exp Otorhinolaryngol. 2018;11(2):146-150.

This study is a prospective randomized trial of the effect of propolis on wound healing process after tonsillectomy.
Post-tonsillectomy pain was significantly less in propolis group compared to control group on postoperative days 3 and 7–10.
The wound healing was significantly better in the propolis group compared to the control group on postoperative day 7–10.
Post-tonsillectomy hemorrhage was significantly less in the propolis group compared to the control group

Current Issue: Volume 11(2); Jun 2018

Samter’s Triad: State of the Art Sung-Dong Kim, Kyu-Sup Cho Clin Exp Otorhinolaryngol. 2018;11(2):71-80. Review April 13, 2018 Full text PubReader ePub PDF	A Systematic Review of Benefit of Silicone Intubation in Endoscopic Dacryocystorhinostomy Min Gyu Kang, Woo Sub Shim, Dong Keun Shin, Joo Yeon Kim, Ji-Eun Lee, Hahn Jin Jung Clin Exp Otorhinolaryngol. 2018;11(2):81-88. Review April 14, 2018 Full text PubReader ePub PDF
Endoscope-Assisted Cochlear Implantation Enis Alpin Güneri, Yüksel Olgun Clin Exp Otorhinolaryngol. 2018;11(2):89-95. Original Article December 1, 2017 Full text PubReader ePub PDF	Clinical Characteristics and Short-term Outcomes of Acute Low Frequency Sensorineural Hearing Loss With Vertigo Myung Jin Park, Sang Hoon Kim, Sung Su Kim, Seung Geun Yeo Clin Exp Otorhinolaryngol. 2018;11(2):96-101. Original Article January 10, 2018 Full text PubReader ePub PDF
Relationship of Vertigo and Postural Instability in Patients With Vestibular Schwannoma Gi-Sung Nam, Chan Min Jung, Ji Hyung Kim, Eun Jin Son Clin Exp Otorhinolaryngol. 2018;11(2):102-108. Original Article January 9, 2018 Full text PubReader ePub PDF	Impact of Nicotine Exposure on Hair Cell Toxicity and Embryotoxicity During Zebrafish Development Myung Hoon Yoo, Yoon Chan Rah, Saemi Park, Soonil Koun, Gi Jung Im, Sung Won Chae, Hak Hyun Jung, June Choi Clin Exp Otorhinolaryngol. 2018;11(2):109-117. Original Article January 6, 2018 Full text PubReader ePub PDF
The Allele 2 of the VNTR Polymorphism in the Gene That Encodes a Natural Inhibitor of IL-1β, IL-1RA Is Favorably Associated With Chronic Otitis Media Maja Živković, Ivana Kolić, Snežana Jesić, Ana Jotić, Aleksandra Stanković Clin Exp Otorhinolaryngol. 2018;11(2):118-123. Original Article February 14, 2018 Full text PubReader ePub PDF	Clusterin Induces MUC5AC Expression via Activation of NF-κB in Human Airway Epithelial Cells Chang Hoon Bae, Hyung Gyun Na, Yoon Seok Choi, Si-Youn Song, Yong-Dae Kim Clin Exp Otorhinolaryngol. 2018;11(2):124-132. Original Article January 11, 2018 Full text PubReader ePub PDF
Impact and Modulations of Peripheral and Edaphic B Cell Subpopulations in Chronic Rhinosinusitis With Nasal Polyposis Pascal Ickrath, Norbert Kleinsasser, Xin Ding, Christian Ginzkey, Niklas Beyersdorf, Thomas Kerkau, Rudolf Hagen, Stephan Hackenberg Clin Exp Otorhinolaryngol. 2018;11(2):133-140. Original Article February 8, 2018 Full text PubReader ePub PDF	Comparison of Characteristics According to Reflux Type in Patients With Laryngopharyngeal Reflux Jun Seok Lee, Ah Ra Jung, Jung Min Park, Myung Jin Park, Young Chan Lee, Young-Gyu Eun Clin Exp Otorhinolaryngol. 2018;11(2):141-145. Original Article October 11, 2017 Full text PubReader ePub PDF
Effect of Topical Propolis on Wound Healing Process After Tonsillectomy: Randomized Controlled Study Jeong Hwan Moon, Min Young Lee, Young-Jun Chung, Chung-Ku Rhee, Sang Joon Lee Clin Exp Otorhinolaryngol. 2018;11(2):146-150. Original Article December 28, 2017 Full text PubReader ePub PDF

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