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Review

September 11, 2018


Robotic and Endoscopic Thyroid Surgery: Evolution and Advances
Kyung Tae, Yong Bae Ji, Chang Myeon Song, Junsun Ryu
Clin Exp Otorhinolaryngol. 2019;12(1):1-11.

• Minimally invasive video-assisted thyroidectomy, transaxillary, bilateral axillo-breast approach, facelift and transoral approaches are in common use today.
• Remote access thyroidectomy is feasible and comparable to conventional thyroidectomy.
• The most important advantage of remote access thyroidectomy is its excellent cosmesis.
• The various approaches have their own advantages and disadvantages.
• Strict patient selection criteria are important.

Review

October 18, 2018


Virtual Reality Simulators for Endoscopic Sinus and Skull Base Surgery: The Present and Future
Do Hyun Kim, Yeonji Kim, Jae-Sung Park, Sung Won Kim
Clin Exp Otorhinolaryngol. 2019;12(1):12-17.

• There is a learning curve associated with endoscopic sinus and skull base surgery.
• Virtual reality simulators can be an effective training tool for novice surgeons in reducing the learning curve.
• Optimized software, custom-made devices, and proper assessment are required in this field.

Original Article

May 3, 2018


Cochlear Damage Caused by the Striking Noise of Titanium Head Golf Driver
Yong-Ho Park, Juyong Chung, Min Young Lee, Doh Young Lee, Young Ho Kim
Clin Exp Otorhinolaryngol. 2019;12(1):18-26.

• Mice with continuous exposure of striking noise recovered from threshold shifts 1–2 weeks after noise exposure.
• Mice with repetitive exposure of striking demonstrated noise threshold shifts remained for 2 weeks after exposure.
• The repetitive exposure resulted in greater hair cell damage than the continuous exposure.
• Overexposure to impact noise caused by hitting of titanium head golf driver may be hazardous to the cochlea, and repetitive exposure may induce greater damage than continuous exposure.

Original Article

June 19, 2018


Clinical Characteristics of Temporal Bone Metastases
Kunho Song, Ki-Wan Park, Jae-Hyung Heo, Ik-Chan Song, Yong-Ho Park, Jin Woong Choi
Clin Exp Otorhinolaryngol. 2019;12(1):27-32.

• The most common primary malignancy with temporal bone metastasis (TBM) was lung cancer and the most common otologic manifestations were facial palsy and hearing loss which were similar to those of chronic otitis media.
• Most TBMs occurred late in the disease process after the primary malignancy first metastasized to other organs.
• If otologic manifestations such as facial palsy and hearing loss are presented in patients at advanced stages of malignancy, TBM of primary malignancy should be suspected.
• Hematologic malignancies tend to metastasize to the external auditory canal and the middle ear cleft more commonly than solid cancers do.

Original Article

July 20, 2018


Losartan Prevents Maladaptive Auditory-Somatosensory Plasticity After Hearing Loss via Transforming Growth Factor-β Signaling Suppression
Seog-Kyun Mun, Kyu-Hee Han, Jong Tae Baek, Suk-Won Ahn, Hyun Sang Cho, Mun Young Chang
Clin Exp Otorhinolaryngol. 2019;12(1):33-39.
• Auditory-somatosensory plasticity occurred 2 weeks after hearing loss.
• Losartan prevented auditory-somatosensory plasticity after hearing loss.
• Losartan might prevent axonal sprouting after hearing loss by blocking transforming growth factor-β signaling.

Original Article

July 27, 2018


In Vivo Vibration Measurement of Middle Ear Structure Using Doppler Optical Coherence Tomography: Preliminary Study
Doekmin Jeon, Nam Hyun Cho, Kibeom Park, Kanghae Kim, Mansik Jeon, Jeong Hun Jang, Jeehyun Kim
Clin Exp Otorhinolaryngol. 2019;12(1):40-49.
• Doppler optical coherence tomography is useful for the measurement of the tympanic membrane oscillation in vivo using signal demodulation method.
• The oscillation cycles in normal tympanic membrane for frequencies of the stimuli drum become short in proportional to the frequency of stimuli less than 4 kHz.
• Doppler signal showed a tendency of attenuation in all frequencies, which was prominent at 1 kHz and 2 kHz in fluid in middle ear condition.

Original Article

August 9, 2018


Two Compound Heterozygous Were Identified in SLC26A4 Gene in Two Chinese Families With Enlarged Vestibular Aqueduct
Yongbo Yu, Yang Yang, Jie Lu, Yaqiong Jin, Yeran Yang, Enyu Hong, Jin Shi, Feng Chen, Shujing Han, Ping Chu, et al.
Clin Exp Otorhinolaryngol. 2019;12(1):50-57.
• Two novel compound heterozygous were identified in SLC26A4 gene.
• In one patient, the mutations of c.1174A>T and c.1181delTCT co-occurred.
• The c.1023insC mutation in SLC26A4 gene was novel and truncated Pendrin protein.

Original Article

August 24, 2018


Auditory Deficits in Patients With Mild and Moderate Obstructive Sleep Apnea Syndrome: A Speech Syllable Evoked Auditory Brainstem Response Study
Qiuyang Fu, Tao Wang, Yong Liang, Yong Lin, Xiangdong Zhao, Jian Wan, Suxiao Fan
Clin Exp Otorhinolaryngol. 2019;12(1):58-65.
• Auditory dysfunction without abnormal click-evoked auditory brainstem response (click-ABR) might be found in obstructive sleep apnea syndrome (OSAS) patients.
• More speech-evoked ABR (speech-ABR) than click-ABR helps to detect auditory deficits in OSAS patients.
• Therefore, speech-ABR may be a potential biomarker for auditory dysfunction of OSAS patients.

Original Article

September 8, 2018


Is Hyperbaric Oxygen Therapy Effective in Cisplatin-Induced Ototoxicity in Rats?
H. Bengu Cobanoglu, Erkan Vuralkan, Abdullah Arslan, Bengusu Mirasoglu, A. Savas Toklu
Clin Exp Otorhinolaryngol. 2019;12(1):66-71.
• Hyperbaric oxygen (HBO) therapy may have a protective effect for cisplatin-induced ototoxicity.
• Mice with HBO treatment had better signal-to-noise ratio (SNR).
• Simultaneous HBO treatment with cisplatin injection showed better SNR values.

Original Article

September 8, 2018


Prediction of Obstructive Sleep Apnea Based on Respiratory Sounds Recorded Between Sleep Onset and Sleep Offset
Jeong-Whun Kim, Taehoon Kim, Jaeyoung Shin, Goun Choe, Hyun Jung Lim, Chae-Seo Rhee, Kyogu Lee, Sung-Woo Cho
Clin Exp Otorhinolaryngol. 2019;12(1):72-78.
• Analyses included respiratory sounds from all sleep stages, including N1, N2, N3, rapid eye movement, and waking.
• We analyzed quite many patient sounds simultaneously recorded with polysomnography.
• Our binary classifier predicted patients with apnea hypopnea index of ≥15 with sensitivity and specificity of >80% by using respiratory sounds during sleep.

Original Article

September 28, 2018


Principal Clinical Factors Predicting Therapeutic Outcomes After Surgical Drainage of Postoperative Cheek Cysts: Experience From a Single Center
Sung-Woo Cho, Hyun Jung Lim, Yoonjae Song, Young Kang, Jae Hyun Lim, Yung Jin Jeon, Doo Hee Han, Tae-Bin Won, Dong-Young Kim, Hyun Jik Kim
Clin Exp Otorhinolaryngol. 2019;12(1):79-85.
• Postoperative cheek cyst is a late complication of radical maxillary sinus procedures, including the Caldwell-Luc surgery.
• The location (anterior and lateral) of the cyst was correlated to recurrence after drainage.
• The size (small) of the cyst and an open surgical approach are important factors correlated to the residual symptoms observed even after adequate drainage.

Original Article

October 18, 2018


Decellularization of Trachea With Combined Techniques for Tissue-Engineered Trachea Transplantation
Aysegul Batioglu-Karaaltin, Ercüment Ovali, Mehmet V Karaaltin, Murat Yener, Mehmet Yılmaz, Fatma Eyüpoğlu, Yetkin Zeki Yılmaz, Erol Rüştü Bozkurt, Necdet Demir, Esma Konuk, et al.
Clin Exp Otorhinolaryngol. 2019;12(1):86-94.
• The decellularization time of trachea was shortened by using combination of physical, chemical and enzymatic techniques.
• The combination methods included lyophilization, deoxycholic acid, and deoxyribonuclease.
• The combination methods were undergone within only 3 days without excessive influence of matrix.

Original Article

September 22, 2018


Nasality Changes With Age in Normal Korean-Speaking Adults
Jun Xu, Young-Ae Kang, Soo-Kyoung Park, Young Hoon Yoon, Shang Jie Bai, Yong De Jin, Yong Min Kim, Ki-Sang Rha
Clin Exp Otorhinolaryngol. 2019;12(1):95-99.
• With age, nasal cavity volume increased, and nasal resistance decreased.
• Nasalance scores for the passages containing nasal consonants decreased with age.
• The age-related decreases in nasality may result from factors other than changes in the nasal cavity.
Current Issue
Volume 12(1); Feb 2019
Robotic and Endoscopic Thyroid Surgery: Evolution and Advances
Kyung Tae, Yong Bae Ji, Chang Myeon Song, Junsun Ryu
Clin Exp Otorhinolaryngol. 2019;12(1):1-11.

Review

September 11, 2018
Virtual Reality Simulators for Endoscopic Sinus and Skull Base Surgery: The Present and Future
Do Hyun Kim, Yeonji Kim, Jae-Sung Park, Sung Won Kim
Clin Exp Otorhinolaryngol. 2019;12(1):12-17.

Review

October 18, 2018
Cochlear Damage Caused by the Striking Noise of Titanium Head Golf Driver
Yong-Ho Park, Juyong Chung, Min Young Lee, Doh Young Lee, Young Ho Kim
Clin Exp Otorhinolaryngol. 2019;12(1):18-26.

Original Article

May 3, 2018
Clinical Characteristics of Temporal Bone Metastases
Kunho Song, Ki-Wan Park, Jae-Hyung Heo, Ik-Chan Song, Yong-Ho Park, Jin Woong Choi
Clin Exp Otorhinolaryngol. 2019;12(1):27-32.

Original Article

June 19, 2018
Losartan Prevents Maladaptive Auditory-Somatosensory Plasticity After Hearing Loss via Transforming Growth Factor-β Signaling Suppression
Seog-Kyun Mun, Kyu-Hee Han, Jong Tae Baek, Suk-Won Ahn, Hyun Sang Cho, Mun Young Chang
Clin Exp Otorhinolaryngol. 2019;12(1):33-39.

Original Article

July 20, 2018
In Vivo Vibration Measurement of Middle Ear Structure Using Doppler Optical Coherence Tomography: Preliminary Study
Doekmin Jeon, Nam Hyun Cho, Kibeom Park, Kanghae Kim, Mansik Jeon, Jeong Hun Jang, Jeehyun Kim
Clin Exp Otorhinolaryngol. 2019;12(1):40-49.

Original Article

July 27, 2018
Two Compound Heterozygous Were Identified in SLC26A4 Gene in Two Chinese Families With Enlarged Vestibular Aqueduct
Yongbo Yu, Yang Yang, Jie Lu, Yaqiong Jin, Yeran Yang, Enyu Hong, Jin Shi, Feng Chen, Shujing Han, Ping Chu, et al.
Clin Exp Otorhinolaryngol. 2019;12(1):50-57.

Original Article

August 9, 2018
Auditory Deficits in Patients With Mild and Moderate Obstructive Sleep Apnea Syndrome: A Speech Syllable Evoked Auditory Brainstem Response Study
Qiuyang Fu, Tao Wang, Yong Liang, Yong Lin, Xiangdong Zhao, Jian Wan, Suxiao Fan
Clin Exp Otorhinolaryngol. 2019;12(1):58-65.

Original Article

August 24, 2018
Is Hyperbaric Oxygen Therapy Effective in Cisplatin-Induced Ototoxicity in Rats?
H. Bengu Cobanoglu, Erkan Vuralkan, Abdullah Arslan, Bengusu Mirasoglu, A. Savas Toklu
Clin Exp Otorhinolaryngol. 2019;12(1):66-71.

Original Article

September 8, 2018
Prediction of Obstructive Sleep Apnea Based on Respiratory Sounds Recorded Between Sleep Onset and Sleep Offset
Jeong-Whun Kim, Taehoon Kim, Jaeyoung Shin, Goun Choe, Hyun Jung Lim, Chae-Seo Rhee, Kyogu Lee, Sung-Woo Cho
Clin Exp Otorhinolaryngol. 2019;12(1):72-78.

Original Article

September 8, 2018
Principal Clinical Factors Predicting Therapeutic Outcomes After Surgical Drainage of Postoperative Cheek Cysts: Experience From a Single Center
Sung-Woo Cho, Hyun Jung Lim, Yoonjae Song, Young Kang, Jae Hyun Lim, Yung Jin Jeon, Doo Hee Han, Tae-Bin Won, Dong-Young Kim, Hyun Jik Kim
Clin Exp Otorhinolaryngol. 2019;12(1):79-85.

Original Article

September 28, 2018
Decellularization of Trachea With Combined Techniques for Tissue-Engineered Trachea Transplantation
Aysegul Batioglu-Karaaltin, Ercüment Ovali, Mehmet V Karaaltin, Murat Yener, Mehmet Yılmaz, Fatma Eyüpoğlu, Yetkin Zeki Yılmaz, Erol Rüştü Bozkurt, Necdet Demir, Esma Konuk, et al.
Clin Exp Otorhinolaryngol. 2019;12(1):86-94.

Original Article

October 18, 2018
Nasality Changes With Age in Normal Korean-Speaking Adults
Jun Xu, Young-Ae Kang, Soo-Kyoung Park, Young Hoon Yoon, Shang Jie Bai, Yong De Jin, Yong Min Kim, Ki-Sang Rha
Clin Exp Otorhinolaryngol. 2019;12(1):95-99.

Original Article

September 22, 2018
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