Clinical and Experimental Otorhinolaryngology

Therapeutic Benefits of Vernonia amygdalina in the Treatment of Inflammation and Its Associated Diseases

Du-Bois Asante, Gideon Akuamoah Wiafe, Korantema Mawuena Tsegah, Nelson Kwabla Domey

Clinical Complementary Medicine and Pharmacology.2024; 4(1): 100122. CrossRef

Microbubble-assisted ultrasound for inner ear drug delivery

Fabrice Micaletti, Jean-Michel Escoffre, Sandrine Kerneis, Ayache Bouakaz, John J. Galvin, Luc Boullaud, David Bakhos

Advanced Drug Delivery Reviews.2024; 204: 115145. CrossRef

Role of cytokines and Th17/Tregs imbalance in the pathogenesis of otitis media with effusion. Modulation of Notch1/Hes1/mTORC1/S6k1 signalling pathway underlies the protective effect of astaxanthin

Noura Mostafa Mohamed, Amira Mohamed Abdelhamid, Mohamed Aref, Marwa Abdelhafeez, Hadil Faris Alotabi, Doaa Sayed Mohammed Abdelrahman, Nisreen E. Elwany

International Immunopharmacology.2024; 128: 111521. CrossRef

Immunomodulatory Response of the Middle Ear Epithelial Cells in Otitis Media

David Leffers, Zuzana Penxova, Thorge Kempin, Markus Därr, Jonas Fleckner, Daniela Hollfelder, Allen F. Ryan, Karl-Ludwig Bruchhage, Arwa Kurabi, Anke Leichtle

Otology & Neurotology.2024; 45(3): e248. CrossRef

Otitis media: recent advances in otitis media vaccine development and model systems

Ayesha Zahid, Jennifer C. Wilson, I. Darren Grice, Ian R. Peak

17β‐estradiol Attenuates the Middle Ear Inflammatory Response to Nontypeable Haemophilus influenzae

Pawjai Khampang, Tina L. Samuels, Simon Blaine‐Sauer, Julliette Lucas, Ke Yan, Nikki Johnston, Joseph E. Kerschner

Differential effects of Fucus vesiculosus fucoidan on fibroblast and macrophage cell lines inflammatory activation

Aleksandra Augustyniak, Joanna Przyborska, Helena McMahon

Establishment of novel immortalized middle ear cell lines as models for otitis media

Simon Blaine‐Sauer, Tina L. Samuels, Pawjai Khampang, Ke Yan, Michael E. McCormick, Robert H. Chun, Steven A. Harvey, David R. Friedland, Nikki Johnston, Joseph E. Kerschner

Laryngoscope Investigative Otolaryngology.2023; 8(5): 1428. CrossRef

Experimental cholesteatoma: a comparison between spontaneous and induced models

Felipe da Costa Huve, Jefferson André Bauer, Fábio André Selaimen, Maurício Noschang Lopes da Silva, Sady Selaimen da Costa

Brazilian Journal of Otorhinolaryngology.2023; 89(1): 73. CrossRef

Dual red and near-infrared light-emitting diode irradiation ameliorates LPS-induced otitis media in a rat model

Frontiers in Bioengineering and Biotechnology.2023;[Epub] CrossRef

Micro RNAs and Circular RNAs in Different Forms of Otitis Media

Michal Kotowski, Paulina Adamczyk, Jaroslaw Szydlowski

International Journal of Molecular Sciences.2023; 24(7): 6752. CrossRef

The Hyperproliferation Mechanism of Cholesteatoma Based on Proteomics: SNCA Promotes Autophagy-Mediated Cell Proliferation Through the PI3K/AKT/CyclinD1 Signaling Pathway

Miao Gao, Heng Xiao, Yonglan Liang, Huimin Cai, Xiaojing Guo, Jianwei Lin, Suling Zhuang, Jianhua Xu, Shengnan Ye

Molecular & Cellular Proteomics.2023; 22(9): 100628. CrossRef

Effects of Particulate Matter Exposure on the Eustachian Tube and Middle Ear Mucosa of Rats

Hyun Min Lee, Youn-Suk Son, Hyang-Sook Kim, Joo-Young Kim, Seok-Hyun Kim, Jung Hee Lee, Sung-Won Choi, Se-Joon Oh, Soo-Keun Kong, Moo Jin Baek, Il-Woo Lee

Clinical and Experimental Otorhinolaryngology.2023; 16(3): 225. CrossRef

Therapeutic potentials of ononin with mechanistic insights: A comprehensive review

Md. Shimul Bhuia, Mst Asma Aktar, Raihan Chowdhury, Jannatul Ferdous, Md Anisur Rahman, Md Sakib Al Hasan, Muhammad Torequl Islam

Protection of lipopolysaccharide-induced otic injury by a single dose administration of a novel dexamethasone formulation

Silvia Murillo-Cuesta, Ester Lara, Jose M. Bermúdez-Muñoz, Elena Torres-Campos, Lourdes Rodríguez-de la Rosa, Pilar López-Larrubia, Signe R. Erickson, Isabel Varela-Nieto

Translational Medicine Communications.2023;[Epub] CrossRef

The Role of Vitamins A and E Level in Chronic Suppurative Otitis Media with and without Cholesteatoma

Shinta Boesoirie, Wijana Hasansulama, Lina Lasminingrum, Arif Novianto, Vesara Gatera, Nur Aroeman, Thaufiq Boesoirie

Journal of Multidisciplinary Healthcare.2023; Volume 16: 3435. CrossRef

Endoscopic transcanal attico-antrostomy versus endoscopic-assisted canal wall up mastoidectomy in management of localized cholesteatoma: a randomized clinical trial

Waleed Moneir, Ahmed Hemdan, Noha Ahmed El-Kholy, Mohamed El-Kotb, Mohamed El-Okda

European Archives of Oto-Rhino-Laryngology.2022; 279(9): 4371. CrossRef

Design, synthesis, and pharmacological evaluation of novel and selective COX-2 inhibitors based on celecoxib scaffold supported with in vivo anti-inflammatory activity, ulcerogenic liability, ADME profiling and docking study

Khaled R.A. Abdellatif, Eman K.A. Abdelall, Heba A.H. Elshemy, John N. Philoppes, Emad H.M. Hassanein, Nesma M. Kahk

Mesoporous silica nano-adjuvant triggers pro-inflammatory responses in Caco-2/peripheral blood mononuclear cell (PBMC) co-cultures

Maryam Ghasemi, Bita Bakhshi, Reza Khashei, Sara Soudi

Nanobiomedicine.2022; 9: 184954352210883. CrossRef

Potential nanotechnology-based diagnostic and therapeutic approaches for Meniere's disease

Afsaneh Kashizadeh, Christopher Pastras, Navid Rabiee, Masoud Mohseni-Dargah, Payal Mukherjee, Mohsen Asadnia

Nanomedicine: Nanotechnology, Biology and Medicine.2022; 46: 102599. CrossRef

Trans-cortical vessels in the mouse temporal bulla bone are a means to recruit myeloid cells in chronic otitis media and limit peripheral leukogram changes

Ali Azar, Mahmood F. Bhutta, Jorge Del-Pozo, Elspeth Milne, Michael Cheeseman

Antiulcerogenic Potential of the Ethanolic Extract of Ceiba speciosa (A. St.-Hil.) Ravenna Evaluated by In Vitro and In Vivo Studies

Juliana Andréa Dörr, Fernanda Majolo, Luísa Bortoluzzi, Evelin Zen de Vargas, Joana Silva, Manoela Pasini, Stefani Natali Stoll, Rafael Lopes da Rosa, Mariana Moreira Figueira, Márcio Fronza, Walter O. Beys-da-Silva, Alice Martins, Helena Gaspar, Rui P. P

International Journal of Molecular Sciences.2022; 23(24): 15634. CrossRef

Analysis of Inflammatory Signaling in Human Middle Ear Cell Culture Models of Pediatric Otitis Media

Mana Espahbodi, Tina L. Samuels, Caroline McCormick, Pawjai Khampang, Ke Yan, Samuel Marshall, Michael E. McCormick, Robert H. Chun, Steven A. Harvey, David R. Friedland, Nikki Johnston, Joseph E. Kerschner

The Medially-Invasive Cholesteatoma: An Aggressive Subtype of a Common Pathology

Geoffrey Casazza, Matthew L. Carlson, Clough Shelton, Richard K. Gurgel

Annals of Otology, Rhinology & Laryngology.2021; 130(1): 38. CrossRef

Factor XII deficiency in asymptomatic Saudi population: A retrospective cohort study

Fatmah S. Alqahtany, Farjah H. Algahtani, Mashael M. Alshebly, Thamer S. Albegamy, Essam S. Alghamdi, Mohammed A. Alnakhli, Fatimah M. Madkhaly, Abdullah A. Alharbi, Nawaf A. Alqahtani

Saudi Journal of Biological Sciences.2021; 28(3): 2004. CrossRef

The transcriptional landscape of the cultured murine middle ear epithelium in vitro

Apoorva Mulay, Md Miraj K. Chowdhury, Cameron T. James, Lynne Bingle, Colin D. Bingle

The Effect of Oral Montelukast Administration in Cholesteatoma Development and Inflammation: An Experimental Animal Model

Ramazan Ocal, Selda Kargin Kaytez, Nihat Yumusak, Ozlem Akkoca, Hatice Celik, Necmi Arslan

Otology & Neurotology.2021; 42(5): e568. CrossRef

Vibrio cholerae toxin coregulated pilus provokes inflammatory responses in Coculture model of Caco‐2 and peripheral blood mononuclear cells (PBMC) leading to increased colonization

Maryam Ghasemi, Bita Bakhshi, Reza Khashei, Sara Soudi, Mina Boustanshenas

Microbiology and Immunology.2021; 65(6): 238. CrossRef

Hearing Loss in Id1−/−; Id3+/− and Id1+/−; Id3−/− Mice Is Associated With a High Incidence of Middle Ear Infection (Otitis Media)

Qingyin Zheng, Tihua Zheng, Aizhen Zhang, Bin Yan, Bo Li, Zhaoqiang Zhang, Yan Zhang

Herbal bioactives in treatment of inflammation: An overview

Mukta Gupta, Naresh Singh, Monica Gulati, Reena Gupta, Kalvatala Sudhakar, Bhupinder Kapoor

South African Journal of Botany.2021; 143: 205. CrossRef

IL‑1α, IL‑6 and IL‑8 serum values in patients with chronic suppurative otitis media

Roxana Serban, Cristiana Filip, Luminita Radulescu, Minerva Badescu, Magda Badescu, Bogdan Diaconescu, Mihail Cobzeanu, Bogdan Cobzeanu

Experimental and Therapeutic Medicine.2021;[Epub] CrossRef

Educational Case: Burn Injury—Pathophysiology, Classification, and Treatment

Seth I. Noorbakhsh, Eric M. Bonar, Rachel Polinski, Md Shahrier Amin

Academic Pathology.2021; 8: 23742895211057239. CrossRef

Use of a Network-Based Method to Identify Latent Genes Associated with Hearing Loss in Children

Frontiers in Cell and Developmental Biology.2021;[Epub] CrossRef

Expression of tumor necrosis factor Alpha, interleukin-1 and matrix metalloproteinase-9 and pathomorphological changes in acquired middle ear cholesteatoma

Биомедицинска истраживања.2021; 12(1): 29. CrossRef

Audiological characteristics and exploratory treatment of a rare condition of acute-otitis-media-associated sudden sensorineural hearing loss

World Journal of Clinical Cases.2021; 9(36): 11311. CrossRef

The nuclear transcription factor FoxG1 affects the sensitivity of mimetic aging hair cells to inflammation by regulating autophagy pathways

Zu-hong He, Sheng-yu Zou, Ming Li, Fu-ling Liao, Xia Wu, Hai-ying Sun, Xue-yan Zhao, Yu-juan Hu, Dan Li, Xiao-xiang Xu, Sen Chen, Yu Sun, Ren-jie Chai, Wei-jia Kong

Occult otitis media in dogs with chronic otitis externa – magnetic resonance imaging and association with otoscopic and cytological findings

Andrea Lorek, Ruth Dennis, Jan van Dijk, Jeanette Bannoehr

Veterinary Dermatology.2020; 31(2): 146. CrossRef

Role of Macrophage Migration Inhibitory Factor in NLRP3 Inflammasome Expression in Otitis Media

Shin Kariya, Mitsuhiro Okano, Pengfei Zhao, Yukihide Maeda, Yuko Kataoka, Takaya Higaki, Seiichiro Makihara, Jun Nishihira, Tomoyasu Tachibana, Kazunori Nishizaki

Ultrasound-induced microbubble cavitation via a transcanal or transcranial approach facilitates inner ear drug delivery

Ai-Ho Liao, Chih-Hung Wang, Ping-Yu Weng, Yi-Chun Lin, Hao Wang, Hang-Kang Chen, Hao-Li Liu, Ho-Chiao Chuang, Cheng-Ping Shih

InnovAiT: Education and inspiration for general practice.2020; 13(5): 281. CrossRef

Rescue role of hesperidin in 4-vinylcyclohexene diepoxide-induced toxicity in the brain, ovary and uterus of wistar rats

Amos O. Abolaji, Marvis U. Omozokpia, Olajide J. Oluwamuyide, Temidayo E. Akintola, Ebenezer O. Farombi

Journal of Basic and Clinical Physiology and Pharmacology.2020;[Epub] CrossRef

Characterization, pro-inflammatory response and cytotoxic profile of bioaerosols from urban and rural residential settings in Pune, India

Ritwika Roy, Rohi Jan, Uttara Joshi, Renuka Bhor, Kalpana Pai, P. Gursumeeran Satsangi

Environmental Pollution.2020; 264: 114698. CrossRef

Autophagy Is Deficient and May be Negatively Regulated by SERPINB3 in Middle Ear Cholesteatoma

Kuen-Yao Ho, Chih-Jen Huang, Chih-Chang Hung, Yu-Rong Wu, Chien-Chih Chiu, Chen-Yu Chien, Hsun-Mo Wang, Ning-Chia Chang, I-Ling Lin, Jeff Yi-Fu Chen

Otology & Neurotology.2020; 41(7): e881. CrossRef

Extensive qPCR analysis reveals altered gene expression in middle ear mucosa from cholesteatoma patients

Cecilia Drakskog, Nele de Klerk, Johanna Westerberg, Elina Mäki-Torkko, Susanna Kumlien Georén, Lars Olaf Cardell, Rafael da Costa Monsanto

Niche- and Gender-Dependent Immune Reactions in Relation to the Microbiota Profile in Pediatric Patients with Otitis Media with Effusion

Frida Enoksson, Alicia Ruiz Rodriguez, Chikondi Peno, Carlos Balcazar Lopez, Fredrik Tjernström, Debby Bogaert, Anders P. Hakansson, Caroline Bergenfelz, Andreas J Bäumler

Relationship between clinicopathological characteristics and CYLD expression in patients with cholesteatoma

Shunsuke Miyake, Toru Miwa, Go Yoneda, Ayumi Kanemaru, Haruki Saito, Ryosei Minoda, Yorihisa Orita, Hideyuki Saito, Hirofumi Jono, Ramin Massoumi

Fractalkine (CX3CL1) and its receptor (CX3CR1) in children with hypertrophic adenoid and chronic otitis media with effusion

Serhat Inan, Seda Türkoğlu Babakurban, Selim Sermed Erbek, Yunus Kasım Terzi, Feride Iffet Sahin

Turkish Journal of Biochemistry.2020; 45(1): 44. CrossRef

Cellular content plays a crucial role in Non‐typeableHaemophilus influenzaeinfection of preinflamedJunbomouse middle ear

Pratik P. Vikhe, Tom Purnell, Steve D.M. Brown, Derek W. Hood

Cellular Microbiology.2019; 21(1): e12960. CrossRef

COX-1/COX-2 inhibition assays and histopathological study of the new designed anti-inflammatory agent with a pyrazolopyrimidine core

Eman K.A. Abdelall, Phoebe F. Lamie, Amira K.M. Ahmed, EL-Shaymaa EL-Nahass

A nanoliter resolution implantable micropump for murine inner ear drug delivery

Farzad Forouzandeh, Xiaoxia Zhu, Ahmed Alfadhel, Bo Ding, Joseph P. Walton, Denis Cormier, Robert D. Frisina, David A. Borkholder

Journal of Controlled Release.2019; 298: 27. CrossRef

Comprehensive Detection of Respiratory Bacterial and Viral Pathogens in the Middle Ear Fluid and Nasopharynx of Pediatric Patients With Acute Otitis Media

The Pediatric Infectious Disease Journal.2019; 38(12): 1199. CrossRef

Current management of children with acute otitis media: a feasibility survey for a pragmatic study

Respati Wulansari Ranakusuma, Amanda R. McCullough, Elaine M. Beller, Christopher B. Del Mar, Eka Dian Safitri, Yupitri Pitoyo, Widyaningsih Widyaningsih

Paediatrica Indonesiana.2019; 59(6): 303. CrossRef

Nontypeable Haemophilus influenzae lysates increase heterogeneous nuclear ribonucleoprotein secretion and exosome release in human middle‐ear epithelial cells

Stephanie Val, Anna Krueger, Marian Poley, Ariella Cohen, Kristy Brown, Aswini Panigrahi, Diego Preciado

Expression of Prostaglandin E2 Receptors in Acquired Middle Ear Cholesteatoma

Sujie Wang, Li Xie, Yanfei Zhang, Pengfei Xu, Aiguo Liu

Clinical and Experimental Otorhinolaryngology.2018; 11(1): 17. CrossRef

Systemic corticosteroids for acute otitis media in children

Respati W Ranakusuma, Yupitri Pitoyo, Eka D Safitri, Sarah Thorning, Elaine M Beller, Sudigdo Sastroasmoro, Chris B Del Mar

Cochrane Database of Systematic Reviews.2018;[Epub] CrossRef

The Role of Mannose-Binding Lectin Serum Level in Tubotympanic Chronic Suppurative Otitis Media

Anton Budhi Darmawan, Marsetyawan H. N. E. Soesatyo, Ratna Dwi Restuti, Agus Surono

International Journal of Otolaryngology.2018; 2018: 1. CrossRef

Intrauterine Malnutrition Reduced Long Leptin Receptor Isoform Expression and Proinflammatory Cytokine Production in Male Rat Pulmonary Endothelial Cells Stimulated by Lipopolysaccharide

Aleksandro M. Balbino, Marina M. Silva, Gabriela A. Azevedo, Noemi L. Gil, Renaide R. Ferreira, Leila A. dos Santos, Rebéca M. Gasparin, Liliam Fernandes, Maristella A. Landgraf, Richardt G. Landgraf

Mediators of Inflammation.2018; 2018: 1. CrossRef

Azithromycin and Sensorineural Hearing Loss in Adults: A Retrospective Cohort Study

Adel Alrwisan, Patrick J. Antonelli, Babette A. Brumback, Yu-Jung Wei, Almut G. Winterstein

Oral prednisolone for acute otitis media in children: protocol of a pilot randomised, open-label, controlled study (OPAL study)

Respati W. Ranakusuma, Amanda R. McCullough, Eka D. Safitri, Yupitri Pitoyo, Widyaningsih, Christopher B. Del Mar, Elaine M. Beller

Pilot and Feasibility Studies.2018;[Epub] CrossRef

An Integrative Model Accounting for the Symptom Cluster Triggered After an Acoustic Shock

Arnaud J. Noreña, Philippe Fournier, Alain Londero, Damien Ponsot, Nicolas Charpentier

Trends in Hearing.2018; 22: 233121651880172. CrossRef

NLRP3 inflammasome expression in lipopolysaccharide-induced otitis media

Shin Kariya, Mitsuhiro Okano, Pengfei Zhao, Yukihide Maeda, Yuko Kataoka, Takaya Higaki, Yohei Noda, Seiichiro Makihara, Kazunori Nishizaki

Acta Oto-Laryngologica.2018; 138(12): 1061. CrossRef

Methanol extract of Guettarda speciosa Linn. inhibits the production of inflammatory mediators through the inactivation of Syk and JNK in macrophages

International Journal of Molecular Medicine.2018;[Epub] CrossRef

MCMV triggers ROS/NLRP3-associated inflammasome activation in the inner ear of mice and cultured spiral ganglion neurons, contributing to sensorineural hearing loss

Wei Zhuang, Caiji Wang, Xi Shi, Shiwei Qiu, Shili Zhang, Bing Xu, Min Chen, Wen Jiang, Hongyan Dong, Yuehua Qiao

International Journal of Molecular Medicine.2018;[Epub] CrossRef

Peptides actively transported across the tympanic membrane: Functional and structural properties

Arwa Kurabi, Kerry A. Beasley, Lisa Chang, James McCann, Kwang Pak, Allen F. Ryan, Bernd Sokolowski

Expression of C-type lectin receptor mRNA in chronic otitis media with cholesteatoma

Sang Hoon Kim, Seung-Ho Han, Jae Yong Byun, Moon Suh Park, Young Il Kim, Seung Geun Yeo

Acta Oto-Laryngologica.2017; 137(6): 581. CrossRef

Acute otitis media associated bilateral sudden hearing loss: case report and literature review

The Journal of Laryngology & Otology.2017; 131(S2): S57. CrossRef

Aminophylline restores glucocorticoid sensitivity in a guinea pig model of sudden sensorineural hearing loss induced by lipopolysaccharide

Qiong-Qiong Zhou, Yan-Hong Dai, Xiao-Ping Du, Jie Hou, Hui Qi, Wan-Dong She

Cytokeratin 13, Cytokeratin 17, and Ki-67 Expression in Human Acquired Cholesteatoma and Their Correlation With Its Destructive Capacity

Mahmood A. Hamed, Seiichi Nakata, Kazuya Shiogama, Kenji Suzuki, Ramadan H. Sayed, Yoichi Nishimura, Noboru Iwata, Kouhei Sakurai, Badawy S. Badawy, Ken-ichi Inada, Hayato Tsuge, Yutaka Tsutsumi

Clinical and Experimental Otorhinolaryngology.2017; 10(3): 213. CrossRef

Non‐Typeable Haemophilus influenzae Infection of the Junbo Mouse

Current Protocols in Mouse Biology.2017; 7(1): 29. CrossRef

Is endoscopic ear surgery an alternative to the modified Bondy technique for limited epitympanic cholesteatoma?

Sampath Chandra Prasad, Annalisa Giannuzzi, Eyad Abu Nahleh, Giuseppe De Donato, Alessandra Russo, Mario Sanna

European Archives of Oto-Rhino-Laryngology.2016; 273(9): 2533. CrossRef

Transcanal endoscopic myringoplasty: a case series in a university center

Leandro de Borborema Garcia, Guilherme Figner Moussalem, José Santos Cruz de Andrade, João Mangussi-Gomes, Oswaldo Laércio Mendonça Cruz, Norma de Oliveira Penido, José Ricardo Gurgel Testa

Brazilian Journal of Otorhinolaryngology.2016; 82(3): 321. CrossRef

Expression of macrophage migration inhibitory factor and CD74 in the inner ear and middle ear in lipopolysaccharide-induced otitis media

Hisashi Ishihara, Shin Kariya, Mitsuhiro Okano, Pengfei Zhao, Yukihide Maeda, Kazunori Nishizaki

Acta Oto-Laryngologica.2016; 136(10): 1011. CrossRef

Pathogenesis and Bone Resorption in Acquired Cholesteatoma: Current Knowledge and Future Prospectives

Mahmood A. Hamed, Seiichi Nakata, Ramadan H. Sayed, Hiromi Ueda, Badawy S. Badawy, Yoichi Nishimura, Takuro Kojima, Noboru Iwata, Ahmed R. Ahmed, Khalid Dahy, Naoki Kondo, Kenji Suzuki

Clinical and Experimental Otorhinolaryngology.2016; 9(4): 298. CrossRef

Proteomic Characterization of Middle Ear Fluid Confirms Neutrophil Extracellular Traps as a Predominant Innate Immune Response in Chronic Otitis Media

Stephanie Val, Marian Poley, Kristy Brown, Rachel Choi, Stephanie Jeong, Annie Colberg-Poley, Mary C. Rose, Karuna C. Panchapakesan, Joe C. Devaney, Marcos Perez-Losada, Diego Preciado, Nades Palaniyar

Calcium Metabolism Profile in Rat Inner Ear Indicated by MRI After Tympanic Medial Wall Administration of Manganese Chloride

Annals of Otology, Rhinology & Laryngology.2016; 125(1): 53. CrossRef

Biofilm’s Role in Chronic Cholesteatomatous Otitis Media

Jacopo Galli, Lea Calò, Monica Giuliani, Bruno Sergi, Daniela Lucidi, Duino Meucci, Ezio Bassotti, Maurizio Sanguinetti, Gaetano Paludetti

Otolaryngology–Head and Neck Surgery.2016; 154(5): 914. CrossRef

Systemic corticosteroids for acute otitis media in children

Respati W Ranakusuma, Yupitri Pitoyo, Eka D Safitri, Sarah Thorning, Elaine M Beller, Sudigdo Sastroasmoro, Chris B Del Mar

Cochrane Database of Systematic Reviews.2016;[Epub] CrossRef

A new model for non-typeableHaemophilus influenzaemiddle ear infection in theJunbomutant mouse

Derek Hood, Richard Moxon, Tom Purnell, Caroline Richter, Debbie Williams, Ali Azar, Michael Crompton, Sara Wells, Martin Fray, Steve D. M. Brown, Michael T. Cheeseman

Disease Models & Mechanisms.2016; 9(1): 69. CrossRef

An in vitro model of murine middle ear epithelium

Apoorva Mulay, Khondoker Akram, Debbie Williams, Hannah Armes, Catherine Russell, Derek Hood, Stuart Armstrong, James P. Stewart, Steve D. M. Brown, Lynne Bingle, Colin D. Bingle

Infectious Causes of Cholesteatoma and Treatment of Infected Ossicles prior to Reimplantation by Hydrostatic High-Pressure Inactivation

Wycliffe Omurwa Masanta, Rebecca Hinz, Andreas Erich Zautner

BioMed Research International.2015; 2015: 1. CrossRef

Sensitivity of spiral ganglion neurons to damage caused by mobile phone electromagnetic radiation will increase in lipopolysaccharide-induced inflammation in vitro model

Wen-Qi Zuo, Yu-Juan Hu, Yang Yang, Xue-Yan Zhao, Yuan-Yuan Zhang, Wen Kong, Wei-Jia Kong

Journal of Neuroinflammation.2015;[Epub] CrossRef

Current concepts in the pathogenesis and treatment of chronic suppurative otitis media

Rahul Mittal, Christopher V. Lisi, Robert Gerring, Jeenu Mittal, Kalai Mathee, Giri Narasimhan, Rajeev K. Azad, Qi Yao, M'hamed Grati, Denise Yan, Adrien A. Eshraghi, Simon I. Angeli, Fred F. Telischi, Xue-Zhong Liu

Journal of Medical Microbiology.2015; 64(10): 1103. CrossRef

Lipopolysaccharide-Induced Middle Ear Inflammation Disrupts the cochlear Intra-Strial Fluid–Blood Barrier through Down-Regulation of Tight Junction Proteins

Jinhui Zhang, Songlin Chen, Zhiqiang Hou, Jing Cai, Mingmin Dong, Xiaorui Shi, Binu Tharakan

Control of Middle Ear Inflammatory and Ion Homeostasis Genes by Transtympanic Glucocorticoid and Mineralocorticoid Treatments

Jessyka G. Lighthall, J. Beth Kempton, Frances Hausman, Carol J. MacArthur, Dennis R. Trune, Jan Peter Tuckermann

ALH-L1005 attenuates endotoxin induced inner ear damage

Chul Ho Jang, Yong Beom Cho, Cheol Hee Choi, Yoon Seok Jang, Sook Jin Jang, Won-Kyo Jung, Byung Young Park, Min Young Kim

International Journal of Pediatric Otorhinolaryngology.2014; 78(3): 465. CrossRef

Activation of the EGFR/Akt/NF-κB/cyclinD1 survival signaling pathway in human cholesteatoma epithelium

Wei Liu, Tuanfang Yin, Jihao Ren, Lihua Li, Zian Xiao, Xing Chen, Dinghua Xie

European Archives of Oto-Rhino-Laryngology.2014; 271(2): 265. CrossRef

NOD2/RICK-Dependent β-Defensin 2 Regulation Is Protective for Nontypeable Haemophilus influenzae-Induced Middle Ear Infection

Jeong-Im Woo, Sejo Oh, Paul Webster, Yoo Jin Lee, David J. Lim, Sung K. Moon, Jürgen Harder

Deletion of the Complement C5a Receptor Alleviates the Severity of Acute Pneumococcal Otitis Media following Influenza A Virus Infection in Mice

Hua Hua Tong, Garrett Lambert, Yong Xing Li, Joshua M. Thurman, Gregory L. Stahl, Kelsey Douthitt, Caitlin Clancy, Yujuan He, Andrew S. Bowman, Dennis W. Metzger

In Vitro Interaction of Pseudomonas aeruginosa with Human Middle Ear Epithelial Cells

Rahul Mittal, M’hamed Grati, Robert Gerring, Patricia Blackwelder, Denise Yan, Jian-Dong Li, Xue Zhong Liu, Min Wu

The Role of EGFR/PI3K/Akt/cyclinD1 Signaling Pathway in Acquired Middle Ear Cholesteatoma

Wei Liu, Hongmiao Ren, Jihao Ren, Tuanfang Yin, Bing Hu, Shumin Xie, Yinghuan Dai, Weijing Wu, Zian Xiao, Xinming Yang, Dinghua Xie

Mediators of Inflammation.2013; 2013: 1. CrossRef

Upregulation of Phosphorylated HSP27, PRDX2, GRP75, GRP78 and GRP94 in Acquired Middle Ear Cholesteatoma Growth

Kuen Ho, Tai Yeh, Han Huang, Kuo Hung, Chee Chai, Wan Chen, Shih Tsai, Ning Chang, Chen Chien, Hsun Wang, Yu Wu

International Journal of Molecular Sciences.2013; 14(7): 14439. CrossRef

NTHi induction of Cxcl2 and middle ear mucosal metaplasia in mice

Diego Preciado, Katelyn Burgett, Svetlana Ghimbovschi, Mary Rose

Neutralizing antibody against granulocyte/macrophage colony–stimulating factor inhibits inflammatory response in experimental otitis media

Shin Kariya, Mitsuhiro Okano, Takaya Higaki, Seiichiro Makihara, Takenori Haruna, Motoharu Eguchi, Kazunori Nishizaki

Acquired cholesteatoma: summary of the cascade of molecular events

The Journal of Laryngology & Otology.2013; 127(6): 542. CrossRef

Inner Ear Tissue Remodeling and Ion Homeostasis Gene Alteration in Murine Chronic Otitis Media

Carol J. MacArthur, Fran Hausman, J. Beth Kempton, Nathan Sautter, Dennis R. Trune

IL-32γ Inhibits Acetaminophen-Induced Acute Hepatotoxicity through Inactivation of NF-κB and Stat1 Signals

Y.R. Kim, Y.S. Jung, Y.H. Lee, C.J. Hwang, J.L. Hwang, C.H. Seok, H.C. Seong, N.Y. Yoon, S.Y. Yeom, S.B. Han, D.Y. Yoon, J.T. Hong

European Journal of Inflammation.2013; 11(3): 663. CrossRef

Cytokine Responses in the Common Cold and Otitis Media

Current Allergy and Asthma Reports.2012; 12(6): 574. CrossRef

HCMV-Encoded UL128 Enhances TNF-α and IL-6 Expression and Promotes PBMC Proliferation Through the MAPK/ERK PathwayIn Vitro

Qi Zheng, Ran Tao, Huihui Gao, Jun Xu, Shiqiang Shang, Ning Zhao

Matrix metalloproteinase inhibitor attenuates cochlear lateral wall damage induced by intratympanic instillation of endotoxin

Cheol Hee Choi, Chul Ho Jang, Yong Bum Cho, Si Young Jo, Min Young Kim, Byung Young Park

International Journal of Pediatric Otorhinolaryngology.2012; 76(4): 544. CrossRef

Otitis Media: Molecular Impact of Inflammation in the Middle and Inner Ear—Cytokines, Steroids, and Ion Homeostasis

C. J. MacArthur, F. Hausman, B. Kempton, J. Lighthall, D. R. Trune

Effects of High Hydrostatic Pressure on Bacterial Growth on Human Ossicles Explanted from Cholesteatoma Patients

Steffen Dommerich, Hagen Frickmann, Jürgen Ostwald, Tobias Lindner, Andreas Erich Zautner, Kathleen Arndt, Hans Wilhelm Pau, Andreas Podbielski, Markus M. Heimesaat

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Murine Middle Ear Inflammation and Ion Homeostasis Gene Expression

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HIF–VEGF Pathways Are Critical for Chronic Otitis Media in Junbo and Jeff Mouse Mutants

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