Clinical and Experimental Otorhinolaryngology

TSLP and HMGB1: Inflammatory Targets and Potential Biomarkers for Precision Medicine in Asthma and COPD

Fabiana Furci, Giuseppe Murdaca, Corrado Pelaia, Egidio Imbalzano, Girolamo Pelaia, Marco Caminati, Alessandro Allegra, Gianenrico Senna, Sebastiano Gangemi

HMGB1 modulation in children with allergic rhinitis

Giorgio CIPRANDI, Laura COLAVITA, Caterina CUPPARI, Maria A. TOSCA

Glycyrrhizin and Mannitol Nasal Therapy: Cytological and Clinical Outcomes in Chronic Rhinitis

Giulio Pagliuca, Veronica Clemenzi, Salvatore Martellucci, Francesco Gazia, Sara Santarsiero, Luigi Farina, Andrea Stolfa, Andrea Gallo

International Archives of Otorhinolaryngology.2023; 27(04): e586. CrossRef

In-Depth Serum Proteomics Reveals the Trajectory of Hallmarks of Cancer in Hepatitis B Virus–Related Liver Diseases

Meng Xu, Kaikun Xu, Shangqi Yin, Cheng Chang, Wei Sun, Guibin Wang, Kai Zhang, Jinsong Mu, Miantao Wu, Baocai Xing, Xiaomei Zhang, Jinyu Han, Xiaohang Zhao, Yajie Wang, Danke Xu, Xiaobo Yu

Molecular & Cellular Proteomics.2023; 22(7): 100574. CrossRef

High mobility group box-1: a potential therapeutic target for allergic rhinitis

European Journal of Medical Research.2023;[Epub] CrossRef

High Mobility Group Box-1 Protein and Interleukin 33 Expression in Allergic Rhinitis

Nongping Zhong, Qing Luo, Xiaoyan Huang, Jieqing Yu, Jing Ye, Jian Zhang

AllergoOncology: Danger signals in allergology and oncology: A European Academy of Allergy and Clinical Immunology (EAACI) Position Paper

Christoph Bergmann, Aurélie Poli, Ioana Agache, Rodolfo Bianchini, Heather J. Bax, Mariana Castells, Silvia Crescioli, David Dombrowicz, Denisa Ferastraoaru, Edda Fiebiger, Hannah J. Gould, Karin Hartmann, Elena Izquierdo, Galateja Jordakieva, Debra H. Jo

CD11b suppresses TLR activation of nonclassical monocytes to reduce primary graft dysfunction after lung transplantation

Melissa Querrey, Stephen Chiu, Emilia Lecuona, Qiang Wu, Haiying Sun, Megan Anderson, Megan Kelly, Sowmya Ravi, Alexander V. Misharin, Daniel Kreisel, Ankit Bharat, G.R. Scott Budinger

Journal of Clinical Investigation.2022;[Epub] CrossRef

Th2 cytokines-DUOX2-ROS-HMGB1 translocation axis is important in the pathogenesis of allergic rhinitis

Hyun Jin Min, Joon Soon Park, Kyung Soo Kim, Seung Yong Park, Honghwan Choi, Ju Hee Seo, Miran Kang, Joo-Heon Yoon, Chang-Hoon Kim, Sehoon Kim, Hyung-Ju Cho

Clara cell 16 KDa protein mitigates house dust mite-induced airway inflammation and damage via regulating airway epithelial cell apoptosis in a manner dependent on HMGB1-mediated signaling inhibition

Meixuan Liu, Jingjing Lu, Qian Zhang, Yunxuan Zhang, Zhongliang Guo

Nasal irrigation with Glycyrrhiza glabra extract for treatment of allergic rhinitis – A study of in vitro, in vivo and clinical trial

Geng-He Chang, Yu-Shih Lin, Ke-Hsin Hsu, Yu-Ching Cheng, Pei-Rung Yang, Ming-Shao Tsai, Yao-Te Tsai, Cheng-Ming Hsu, Pey-Jium Chang, Chung-Sheng Shi, Yao-Hsu Yang, Ching-Yuan Wu

Journal of Ethnopharmacology.2021; 275: 114116. CrossRef

Preparation and Characterization of a Glycyrrhizic Acid-Based Drug Delivery System for Allergen-Specific Immunotherapy

Ekaterina Pashkina, Veronika Evseenko, Natalya Dumchenko, Maxim Zelikman, Alina Aktanova, Maria Bykova, Mikhail Khvostov, Aleksandr Dushkin, Vladimir Kozlov

Association analysis of high-mobility group box-1 protein 1 (HMGB1)/toll-like receptor (TLR) 4 with nasal interleukins in allergic rhinitis patients

Allergoonkologie: was Allergologen und Onkologen voneinander lernen können

High-mobility group box 1 protein participates in acute lung injury by activating protein kinase R and inducing M1 polarization

Ruiting Li, You Shang, Yuan Yu, Ting Zhou, Wei Xiong, Xiaojing Zou

Biomarkers in Pediatric Lung Diseases Including Cystic Fibrosis

Giuseppe Fabio Parisi, Maria Papale, Lucia Tardino, Raffaella Nenna, Fabio Midulla, Salvatore Leonardi

Current Respiratory Medicine Reviews.2020; 15(3): 163. CrossRef

An Overview of HMGB1 and its Potential Role as a Biomarker for RSV Infection

Sara Manti, Caterina Cuppari, Giuseppe Fabio Parisi, Carmelo Salpietro

Current Respiratory Medicine Reviews.2020; 15(3): 205. CrossRef

Inflammation, infection, and allergy of upper airways: new insights from national and real-world studies

Attilio Varricchio, Ignazio La Mantia, Francesco Paolo Brunese, Giorgio Ciprandi

Italian Journal of Pediatrics.2020;[Epub] CrossRef

Adenoidal Immune Response in the Context of Inflammation and Allergy

Ilaria Brambilla, Sara Manti, Salvatore Savasta, Chiara Valsecchi, Silvia Maria Elena Caimmi, Gian Luigi Marseglia, Amelia Licari

Current Respiratory Medicine Reviews.2020; 15(3): 231. CrossRef

Bacteriotherapy with Streptococcus salivarius 24SMB and Streptococcus oralis 89a nasal spray for treatment of upper respiratory tract infections in children: a pilot study on short-term efficacy

Sara Manti, Giuseppe Fabio Parisi, Maria Papale, Amelia Licari, Carmelo Salpietro, Michele Miraglia del Giudice, Gian Luigi Marseglia, Salvatore Leonardi

Italian Journal of Pediatrics.2020;[Epub] CrossRef

Analysis the effect of miR‐141‐3p/HMGB1 in LPS‐induced mucus production and the apoptosis in nasal epithelial cells

The Kaohsiung Journal of Medical Sciences.2020; 36(8): 622. CrossRef

HMGB1 in nasal inflammatory diseases: a reappraisal 30 years after its discovery

Giorgio Ciprandi, Luisa Maria Bellussi, Giulio Cesare Passali, Valerio Damiani, Desiderio Passali

Expert Review of Clinical Immunology.2020; 16(5): 457. CrossRef

An overview of high-mobility group box 1, a potent pro-inflammatory cytokine in asthma

Farzaneh Kianian, Mehri Kadkhodaee, Hamid Reza Sadeghipour, Seyed Morteza Karimian, Behjat Seifi

Journal of Basic and Clinical Physiology and Pharmacology.2020;[Epub] CrossRef

Johnny on the Spot-Chronic Inflammation Is Driven by HMGB1

Carolina M. Gorgulho, Graziela G. Romagnoli, Rosh Bharthi, Michael T. Lotze

Profiling of how nociceptor neurons detect danger – new and old foes

T. Crosson, K. Roversi, M. Balood, R. Othman, M. Ahmadi, J.‐C. Wang, P. J. Seadi Pereira, M. Tabatabaei, R. Couture, T. Eichwald, A. Latini, R.D. Prediger, M. Rangachari, C. R. Seehus, S. L. Foster, S. Talbot

Journal of Internal Medicine.2019; 286(3): 268. CrossRef

HMGB1 participates in LPS‑induced acute lung injury by�activating the AIM2 inflammasome in macrophages�and inducing polarization of M1 macrophages via TLR2, TLR4, and RAGE/NF‑κB signaling pathways

Jing Wang, Ruiting Li, Zhiyong Peng, Bo Hu, Xin Rao, Jianguo Li

International Journal of Molecular Medicine.2019;[Epub] CrossRef

HMGB1 regulates T helper 2 and T helper17 cell differentiation both directly and indirectly in asthmatic mice

Ruiting Li, Jing Wang, Fangfang Zhu, Ruifang Li, Bing Liu, Wenjuan Xu, Guangzhen He, Huan Cao, Yimin Wang, Jiong Yang

Glycyrrhizin ameliorates atopic dermatitis-like symptoms through inhibition of HMGB1

International Immunopharmacology.2018; 60: 9. CrossRef

HMGB1 knock‐down promoting tumor cells viability and arrest pro‐apoptotic proteins via Stat3/NFκB in HepG2 cells

Salah Alduais, Yaser Alduais, Xiaolei Wu, Haosen Li, Jing Mao

HMGB1 as a new biomarker of celiac disease in children: A multicenter study

Sara Manti, Caterina Cuppari, Lucia Tardino, Giuseppe Parisi, Massimo Spina, Carmelo Salpietro, Salvatore Leonardi

Emerging Endotypes of Chronic Rhinosinusitis and Its Application to Precision Medicine

Allergy, Asthma & Immunology Research.2017; 9(4): 299. CrossRef

Association between HMGB1 and asthma: a literature review

Egidio Imbalzano, Sebastiano Quartuccio, Eleonora Di Salvo, Teresa Crea, Marco Casciaro, Sebastiano Gangemi

Clinical and Molecular Allergy.2017;[Epub] CrossRef

Nasal Muco-ciliary transport time alteration: efficacy of 18 B Glycyrrhetinic acid

Desiderio Passali, Chiara Cappello, Giulio Cesare Passali, Cemal Cingi, Codrut Sarafoleanu, Luisa Maria Bellussi

Multidisciplinary Respiratory Medicine.2017;[Epub] CrossRef

HMGB1-TLR4 Signaling Contributes to the Secretion of Interleukin 6 and Interleukin 8 by Nasal Epithelial Cells

Shino Shimizu, Hideaki Kouzaki, Tomohisa Kato, Ichiro Tojima, Takeshi Shimizu

American Journal of Rhinology & Allergy.2016; 30(3): 167. CrossRef